CA-4948
CA-4948 (Emavusertib) is a small molecule inhibitor targeting IRAK4 and FLT3 kinases. It has demonstrated anti-tumor activity in preclinical research, showing efficacy in both in vitro cellular assays and in vivo models of hematological malignancies.
Product Specifications
CAS Number
1801344-14-8
Product Name Alternative
Cluster of differentiation antigen 135, CD135, CA 4948, CA-4948, CA4948, arthritis, Inhibitor, FLT3, Fms like tyrosine kinase 3, Emavusertib, Myd88, inhibit, IL-1R, IL-1R associated kinase, Interleukin-1 receptor associated kinase, IRAK, IRAK4, inflammation, lymphoma, rheumatoid, Toll
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
99.35% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.07 mM) ; H2O:< 0.1 mg/mL (insoluble) ; DMSO:27.78 mg/mL (56.52 mM)
Smiles
Cc1cc (ccn1) -c1nc (co1) C (=O) Nc1cc2oc (nc2nc1N1CC[C@@H] (O) C1) N1CCOCC1
Molecular Formula
C24H25N7O5
Molecular Weight
491.5
Storage Conditions
-20°C
Notes
For research use only.
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