AES-350
AES-350 is a potent, orally bioavailable HDAC6 inhibitor with high selectivity. It induces apoptosis in acute myeloid leukemia (AML) cells in vitro and shows potential for in vivo research, making it a valuable tool for oncology and epigenetics studies.
Product Specifications
CAS Number
847249-57-4
Product Name Alternative
Histone deacetylases, Inhibitor, HDAC, HDAC11, HDAC3, HDAC6, MV4-11, inhibit, Apoptosis, AML, acute myeloid leukemia, AES 350, AES350, AES-350
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.82% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.81 mM) ; DMSO:100 mg/mL (320.14 mM)
Smiles
CC (C) (C) c1ccc (cc1) C (=O) Nc1ccc (cc1) C (=O) NO
Molecular Formula
C18H20N2O3
Molecular Weight
312.36
Storage Conditions
-20°C
Notes
For research use only.
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