Lats-IN-1
Lats-IN-1 is a potent, ATP-competitive inhibitor of the kinases Lats1 and Lats2. By inhibiting these kinases, it activates Yap signaling and has been shown to stimulate proliferation in postmitotic mammalian tissues in research settings, making it a valuable tool for studying the Hippo pathway in vitro and in vivo.
Product Specifications
CAS Number
1424635-83-5
Product Name Alternative
YAP, Yes-associated protein, inhibit, Inhibitor, Lats IN 1, Lats1, Lats2, LatsIN1, Lats-IN-1
Field of Research
Stem Cell & Developmental Biology
Purity
97.54% (May vary between batches)
Solubility
DMSO:83.33 mg/mL (249.2 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (9.87 mM)
Smiles
O=C (\N=c1/sccn1Cc1ccccc1) c1c[nH]c2ncccc12
Molecular Formula
C18H14N4OS
Molecular Weight
334.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC228521L4V 200 µL
POU6F2 (NM_001166018) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
GPR65-3888M 50 µg
Recombinant Mouse GPR65 Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details