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Necrostatin-34

Necrostatin-34 is a potent and selective RIPK1 kinase inhibitor that stabilizes the kinase in an inactive state. It is widely used in research to investigate necroptosis in both cellular and animal models of inflammatory and degenerative diseases.

Product Specifications

CAS Number

375835-43-1

Product Name Alternative

Nec-34; 2- ((3-Cyano-6-oxo-4- (p-tolyl) -1,4,5,6-tetrahydropyridin-2-yl) thio) -N- (thiazol-2-yl) acetamide

Field of Research

Cell Biology

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml)

Smiles

Cc1ccc (cc1) C1CC (=O) NC (SCC (=O) Nc2nccs2) =C1C#N

Molecular Formula

C18H16N4O2S2

Molecular Weight

384.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2-[[5-Cyano-4- (4-methylphenyl) -2-oxo-3,4-dihydro-1H-pyridin-6-yl]sulfanyl]-N- (1,3-thiazol-2-yl) acetamide

Available Sizes

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