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ML328

ML328 is a potent, selective small-molecule inhibitor of the bacterial helicase-nucleases AddAB (IC50 = 1.0 μM) and RecBCD (IC50 = 4.8 μM) . This compound is a valuable research tool for studying DNA repair and recombination pathways in vitro, offering insights into bacterial genome maintenance mechanisms.

Product Specifications

CAS Number

634175-34-1

Product Name Alternative

AddAB helicase-nuclease, ML 328, ML328, ML-328, RecBCD helicase-nuclease

Field of Research

Infectious Disease & Virology

Purity

98.14% (May vary between batches)

Solubility

DMSO:50 mg/mL (98.72 mM)

Smiles

C (C) N1C=2C (C (=O) C (C (O) =O) =C1) =CN=C (N2) N3CCN (C (NC4=CC (C (F) (F) F) =CC=C4) =S) CC3

Molecular Formula

C22H21F3N6O3S

Molecular Weight

506.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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