Eclitasertib
Eclitasertib is a potent small molecule RIPK1 inhibitor with an IC50 below 1 μM. It is a valuable research tool for studying necroptosis and inflammation in cellular and animal models of neurodegenerative and inflammatory diseases.
Product Specifications
CAS Number
2125450-76-0
Product Name Alternative
DNL 758, DNL758, DNL-758, inhibit, Eclitasertib, Inhibitor, Receptor-interacting protein kinases, SAR 443122, SAR443122, SAR-443122, RIP kinase, RIPK, RIPK1, RIPkinase
Field of Research
Cell Biology, Signal Transduction
Purity
99.82% (May vary between batches)
Solubility
DMSO:125 mg/mL (330.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.57 mM)
Smiles
CN1c2ncccc2OC[C@H] (NC (=O) c2nnc (Cc3ccccc3) [nH]2) C1=O
Molecular Formula
C19H18N6O3
Molecular Weight
378.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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