BTK inhibitor 17
BTK inhibitor 17 is a potent and irreversible small molecule targeting Bruton's tyrosine kinase with an IC50 of 2.1 nM. It serves as a valuable research tool for investigating rheumatoid arthritis and related autoimmune conditions in both cellular and animal model studies.
Product Specifications
CAS Number
1858206-76-4
Product Name Alternative
Arthritis, BTK inhibitor 17, BTK inhibitor17, BTK inhibitor-17, Btk, BTK, Bruton tyrosine kinase, Cys481, oral, inhibit, Inhibitor, rheumatoid
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
99.29% (May vary between batches)
Solubility
DMSO:100 mg/mL (219.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.76 mM)
Smiles
Nc1n[nH]c (=O) c2n (nc (-c3ccc (Oc4ccccc4) cc3) c12) [C@@H]1CCCN (C1) C (=O) C=C
Molecular Formula
C25H24N6O3
Molecular Weight
456.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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