2'-Fluoro-2'-Deoxyadenosine
2'-Fluoro-2'-Deoxyadenosine is a prodrug efficiently converted to the cytotoxic 2-fluoroadenine by E. coli PNP, demonstrating antitumor activity in vivo. It also serves as a building block for synthesizing 2'-fluoro-modified oligonucleotides, which are useful tools for RNA targeting and hybridization studies.
Product Specifications
CAS Number
64183-27-3
Product Name Alternative
Analog, 2'-Fluoro-2'-Deoxyadenosine, 2'Fluoro2'Deoxyadenosine, 2' Fluoro 2' Deoxyadenosine, oligonucleotide, NucleosideAntimetabolite, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, inhibit, Inhibitor, FAde, purine nucleoside phosphorylase, tumor
Field of Research
Cell Biology, Molecular Biology
Purity
99.35% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.43 mM) ; DMSO:50 mg/mL (185.71 mM)
Smiles
Nc1ncnc2n (cnc12) [C@@H]1O[C@H] (CO) [C@@H] (O) [C@H]1F
Molecular Formula
C10H12FN5O3
Molecular Weight
269.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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