VY-3-135
VY-3-135 is a potent and selective oral ACSS2 inhibitor (IC50 = 44 nM) with no activity against ACSS1/ACSS3. It effectively blocks ACSS2-dependent fatty acid metabolism in vitro and in vivo, making it a valuable tool for researching cancer metabolism and metabolic disorders.
Product Specifications
CAS Number
1824637-41-3
Product Name Alternative
Breast cancer, ACSS2, Inhibitor, FattyAcidSynthase, Fatty Acid Synthase, inhibit, orally active, stable ACSS2 inhibitor, VY3135, VY-3-135, VY 3 135
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:46.67 mg/mL (108.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)
Smiles
CCn1c (nc2ccc (cc12) C (=O) NC[C@@H] (C) O) C (O) (c1ccccc1) c1ccccc1
Molecular Formula
C26H27N3O3
Molecular Weight
429.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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