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VY-3-135

VY-3-135 is a potent and selective oral ACSS2 inhibitor (IC50 = 44 nM) with no activity against ACSS1/ACSS3. It effectively blocks ACSS2-dependent fatty acid metabolism in vitro and in vivo, making it a valuable tool for researching cancer metabolism and metabolic disorders.

Product Specifications

CAS Number

1824637-41-3

Product Name Alternative

Breast cancer, ACSS2, Inhibitor, FattyAcidSynthase, Fatty Acid Synthase, inhibit, orally active, stable ACSS2 inhibitor, VY3135, VY-3-135, VY 3 135

Field of Research

Metabolism Research

Purity

98.00% (May vary between batches)

Solubility

DMSO:46.67 mg/mL (108.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)

Smiles

CCn1c (nc2ccc (cc12) C (=O) NC[C@@H] (C) O) C (O) (c1ccccc1) c1ccccc1

Molecular Formula

C26H27N3O3

Molecular Weight

429.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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