SETDB1-TTD-IN-1
SETDB1-TTD-IN-1 is a potent and selective inhibitor of the SETDB1 tandem tudor domain (TTD), exhibiting high affinity with a Kd of 88 nM. This compound serves as a valuable chemical probe for investigating the role of SETDB1 in epigenetic regulation, facilitating both in vitro biochemical and cellular studies of its function in oncology and neurobiology research.
Product Specifications
CAS Number
2755823-12-0
Product Name Alternative
Histone Methyltransferase, HistoneMethyltransferase, SETDB1 TTD IN 1, SETDB1-TTD, SETDB1TTDIN1, SETDB-1-TTD-IN-1, SETDB1-TTD-IN-1
Field of Research
Epigenetics & Chromatin
Purity
98.26% (May vary between batches)
Solubility
DMSO:252.5 mg/mL (537.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.65 mM)
Smiles
CN1C[C@@H] (C[C@@H] (C1) c1ccc (OCc2ccccc2) cc1) Nc1nc2cc[nH]c2c (=O) n1CC=C
Molecular Formula
C28H31N5O2
Molecular Weight
469.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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