FHD-286
FHD-286 is a potent and selective ATPase inhibitor of the SWI/SNF chromatin remodeling complex subunits BRM (SMARCA2) and BRG1 (SMARCA4) . It serves as a valuable chemical probe for investigating BAF complex dysfunction in diseases, supporting both in vitro mechanistic studies and in vivo research in models of acute myeloid leukemia.
Product Specifications
CAS Number
2671128-05-3
Product Name Alternative
Inhibit, Inhibitor, FHD 286, FHD286, FHD-286, Epigenetic Reader Domain, EpigeneticReaderDomain, BRM/BRG1
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.70% (May vary between batches)
Solubility
DMSO:245 mg/mL (435.43 mM)
Smiles
COC[C@H] (NC (=O) c1ccn (c1) S (C) (=O) =O) C (=O) Nc1nc (cs1) -c1cccc (n1) N1C[C@H] (C) O[C@H] (C) C1
Molecular Formula
C24H30N6O6S2
Molecular Weight
562.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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