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LEI110

LEI110 is a potent and selective pan-inhibitor of the HRASLS thiol hydrolase family, including PLA2G16 (Ki=20 nM), HRASLS2, RARRES3, and iNAT. This small molecule is a valuable research tool for studying lipid metabolism and signaling in both cellular and animal models of metabolic disorders and cancer.

Product Specifications

CAS Number

2313525-90-3

Product Name Alternative

Inhibit, lipolysis, Inhibitor, HepG2 cells, LEI 110, LEI110, LEI-110, thiol hydrolases, PLA2G16, Phospholipase

Field of Research

Metabolism Research

Purity

97.56% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2.5 mg/mL (5.48 mM) ; DMSO:50 mg/mL (109.54 mM)

Smiles

FC (F) (F) c1ccc (Oc2ccc (CCNC (=O) C (=O) CCCc3ccccc3) cc2) nc1

Molecular Formula

C25H23F3N2O3

Molecular Weight

456.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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