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E3 ligase Ligand 23

Ligand 23 is a cereblon E3 ligase-binding molecule that induces the ubiquitin-proteasomal degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) . This mechanism of action makes it a valuable chemical probe for studying immunology and oncology in both cellular and animal models of disease.

Product Specifications

CAS Number

444287-56-3

Product Name Alternative

E3 ligase-recruiting Moiety, E3 ligase Ligand 23, E-3 ligase Ligand 23, Cereblon, Aiolos, Inhibitor, Ligand for E3 Ligase, LigandforE3Ligase, Ligands for E3 Ligase, inhibit, Ikaros, ubiquitin proteasome

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Purity

98.49% (May vary between batches)

Solubility

DMSO:55 mg/mL (151.36 mM)

Smiles

N (CC1=CC=CC=C1) C2=C3C (C (=O) N (C3=O) C4C (=O) NC (=O) CC4) =CC=C2

Molecular Formula

C20H17N3O4

Molecular Weight

363.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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