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GDC-0214

GDC-0214 is an investigational, inhaled small molecule that selectively inhibits JAK1. It has been shown to reduce fractional exhaled nitric oxide (FeNO), a biomarker of airway inflammation, in preclinical research relevant to asthma and other respiratory diseases.

Product Specifications

CAS Number

1831144-46-7

Product Name Alternative

GDC 0214, GDC0214, GDC-0214, JAK1

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.54% (May vary between batches)

Solubility

DMSO:9 mg/mL (14.71 mM)

Smiles

N (C (=O) C1=C2N (N=C1) C=CC=N2) C=3C (=NN (CC (=O) N4CCC (N (CCC#N) C) CC4) C3) C5=C (OC (F) F) C=CC (Cl) =C5

Molecular Formula

C28H28ClF2N9O3

Molecular Weight

612.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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