GDC-0214
GDC-0214 is an investigational, inhaled small molecule that selectively inhibits JAK1. It has been shown to reduce fractional exhaled nitric oxide (FeNO), a biomarker of airway inflammation, in preclinical research relevant to asthma and other respiratory diseases.
Product Specifications
CAS Number
1831144-46-7
Product Name Alternative
GDC 0214, GDC0214, GDC-0214, JAK1
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.54% (May vary between batches)
Solubility
DMSO:9 mg/mL (14.71 mM)
Smiles
N (C (=O) C1=C2N (N=C1) C=CC=N2) C=3C (=NN (CC (=O) N4CCC (N (CCC#N) C) CC4) C3) C5=C (OC (F) F) C=CC (Cl) =C5
Molecular Formula
C28H28ClF2N9O3
Molecular Weight
612.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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