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ALK5-IN-10

Compound 12d is a highly effective small molecule inhibitor of ALK5 (TGF-β type I receptor), exhibiting potent activity with a 7 nM IC50. This inhibitor is a valuable research tool for studying TGF-β signaling pathways in both cellular assays and animal models of fibrosis and cancer.

Product Specifications

CAS Number

1352608-94-6

Product Name Alternative

ALK5, N ((4 ([1,2,4]triazolo[1,5 a]pyridin 6 yl) 5 (6 methylpyridin 2 yl) 1H imidazol 2 yl) methyl) 2 bromoaniline, N ((4 ([1,2,4]triazolo[1,5a]pyridin6yl) 5 (6methylpyridin2yl) 1Himidazol2yl) methyl) 2bromoaniline

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.27% (May vary between batches)

Solubility

DMSO:50 mg/mL (108.62 mM)

Smiles

C (NC1=C (Br) C=CC=C1) C=2NC (=C (N2) C=3N=C (C) C=CC3) C4=CN5C (C=C4) =NC=N5

Molecular Formula

C22H18BrN7

Molecular Weight

460.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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