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5- (3-bromo-4,5-dihydroisoxazol-5-yl) -3- (4- (tert-butyl) phenyl)

Antileishmanial agent-2 is a potent 3-bromo-isoxazoline compound exhibiting dual antiparasitic activity. It inhibits Plasmodium falciparum (D10, W2) and Leishmania spp. (L. infantum, L. tropica) promastigotes in vitro with low micromolar IC50 values, making it a candidate for antimalarial and antileishmanial drug discovery research.

Product Specifications

CAS Number

2863687-18-5

Product Name Alternative

5 (3bromo4,5dihydroisoxazol5yl) 3 (4 (tertbutyl) phenyl) 1,2,4oxadiazole, 5 (3 bromo 4,5 dihydroisoxazol 5 yl) 3 (4 (tert butyl) phenyl) 1,2,4 oxadiazole, P. falciparum

Field of Research

Infectious Disease & Virology, Signal Transduction

Purity

99.58% (May vary between batches)

Solubility

DMSO:65 mg/mL (185.6 mM)

Smiles

C (C) (C) (C) C1=CC=C (C=2N=C (ON2) C3ONC (Br) =C3) C=C1

Molecular Formula

C15H16BrN3O2

Molecular Weight

350.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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