Almonertinib mesylate
Almonertinib mesylate is an irreversible, highly selective EGFR tyrosine kinase inhibitor targeting sensitizing and T790M resistance mutations. It is widely used in non-small cell lung cancer (NSCLC) research, with applications in both in vitro biochemical assays and in vivo xenograft models to study efficacy and resistance mechanisms.
Product Specifications
CAS Number
2134096-06-1
Product Name Alternative
Almonertinib, Almonertinib mesylate, Almonertinib Mesylate, irreversible, inhibit, Inhibitor, non-small cell lung cancer, HER1, HS 10296, HS10296, HS-10296, EGFR (T790M), EGFR tyrosine kinase inhibitor, EGFR, EGFR (del19/T790M), EGFR (L858R/T790M), Epidermal growth factor receptor, ErbB-1, third-generation, orally available
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.85% (May vary between batches)
Solubility
DMSO:40 mg/mL (64.33 mM)
Smiles
CS (O) (=O) =O.COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1cn (C2CC2) c2ccccc12
Molecular Formula
C31H39N7O5S
Molecular Weight
621.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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