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CROCONAZOLE

Croconazole, an antimycotic agent, demonstrates dose-dependent inhibition of neutrophil 5-lipoxygenase (5-LOX), with IC50 values of 7.8 μM for LTB4 and 5-HETE synthesis. This activity supports its research use in studying eicosanoid pathways and inflammation in both cellular and biochemical assay systems.

Product Specifications

CAS Number

77175-51-0

Product Name Alternative

CROCONAZOLE, Croconazole, 5-LOX, 5-HETE, LTB4

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.71% (May vary between batches)

Solubility

Acetonitrile:1.55 mg/mL (4.99 mM) ; Methanol:1.55 mg/mL (4.99 mM) ; DMSO:50 mg/mL (160.89 mM)

Smiles

C (=C) (C1=C (OCC2=CC (Cl) =CC=C2) C=CC=C1) N3C=CN=C3

Molecular Formula

C18H15ClN2O

Molecular Weight

310.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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