CROCONAZOLE
Croconazole, an antimycotic agent, demonstrates dose-dependent inhibition of neutrophil 5-lipoxygenase (5-LOX), with IC50 values of 7.8 μM for LTB4 and 5-HETE synthesis. This activity supports its research use in studying eicosanoid pathways and inflammation in both cellular and biochemical assay systems.
Product Specifications
CAS Number
77175-51-0
Product Name Alternative
CROCONAZOLE, Croconazole, 5-LOX, 5-HETE, LTB4
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.71% (May vary between batches)
Solubility
Acetonitrile:1.55 mg/mL (4.99 mM) ; Methanol:1.55 mg/mL (4.99 mM) ; DMSO:50 mg/mL (160.89 mM)
Smiles
C (=C) (C1=C (OCC2=CC (Cl) =CC=C2) C=CC=C1) N3C=CN=C3
Molecular Formula
C18H15ClN2O
Molecular Weight
310.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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