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NSC 370284

NSC 370284 is a direct STAT3/5 inhibitor that selectively targets and reduces the viability of acute myeloid leukemia (AML) cells exhibiting high TET1 expression. Its efficacy has been demonstrated in both cellular assays and animal models, supporting its use as a research tool for studying oncogenic signaling in AML.

Product Specifications

CAS Number

116409-29-1

Product Name Alternative

NSC 370284, NSC370284, NSC-370284, STAT3/5

Field of Research

Epigenetics & Chromatin, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Purity

96.16% (May vary between batches)

Solubility

DMSO:55 mg/mL (141.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.16 mM)

Smiles

COc1cc (cc (OC) c1OC) C (N1CCCC1) c1cc2OCOc2cc1O

Molecular Formula

C21H25NO6

Molecular Weight

387.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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