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K-975

K-975 is a potent and selective oral TEAD inhibitor that disrupts the TEAD-YAP1/TAZ protein-protein interaction. It is used in cancer research, particularly for mesothelioma and other malignancies driven by Hippo pathway dysregulation, and has demonstrated efficacy in both cellular assays and in vivo models.

Product Specifications

CAS Number

2563855-03-6

Product Name Alternative

YAP, TAZ, TEAD, YAP1/TAZ, TEAD, Yes-associated protein, YAP1, pleural, mesothelioma, K975, K-975, K 975, inhibit, malignant, Inhibitor, Cys359, cancer, antitumor

Field of Research

Stem Cell & Developmental Biology

Purity

99.43% (May vary between batches)

Solubility

DMSO:140 mg/mL (486.55 mM)

Smiles

Cc1ccc (NC (=O) C=C) cc1Oc1ccc (Cl) cc1

Molecular Formula

C16H14ClNO2

Molecular Weight

287.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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