K-975
K-975 is a potent and selective oral TEAD inhibitor that disrupts the TEAD-YAP1/TAZ protein-protein interaction. It is used in cancer research, particularly for mesothelioma and other malignancies driven by Hippo pathway dysregulation, and has demonstrated efficacy in both cellular assays and in vivo models.
Product Specifications
CAS Number
2563855-03-6
Product Name Alternative
YAP, TAZ, TEAD, YAP1/TAZ, TEAD, Yes-associated protein, YAP1, pleural, mesothelioma, K975, K-975, K 975, inhibit, malignant, Inhibitor, Cys359, cancer, antitumor
Field of Research
Stem Cell & Developmental Biology
Purity
99.43% (May vary between batches)
Solubility
DMSO:140 mg/mL (486.55 mM)
Smiles
Cc1ccc (NC (=O) C=C) cc1Oc1ccc (Cl) cc1
Molecular Formula
C16H14ClNO2
Molecular Weight
287.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog