2,5-Dihydroxyacetophenone

2,5-Dihydroxyacetophenone (Quinacetophenone) is a bioactive small molecule with neuroprotective, anti-inflammatory, and anti-melanogenic properties. It modulates MAPK signaling, enhances bortezomib effects in myeloma cells, and inhibits tyrosinase, as demonstrated in vitro with B16 melanoma cells and in vivo in zebrafish and mouse models.

Product Specifications

CAS Number

490-78-8

Product Name Alternative

DHAP, Acetylhydroquinone, 2-Acetylhydroquinone, 2-5-dihydroxyacetophenone, 2,5 Dihydroxyacetophenone, 2,5Dihydroxyacetophenone, 2,5-Dihydroxyacetophenone, inflammatory, mRNA, inhibit, p65, LPS-stimulated, Nuclear factor-κB, Nuclear factor-kappaB, NFκB, NF-kB, NFkB, NF-κB, macrophages, ERK, Extracellular signal regulated kinases, IL-6, mediators, Inhibitor, iNOS, Rehmanniae, TNF-α, RAW264.7, Preparata, Radix, Quinacetophenone, Tyrosinase

Field of Research

Protein Biochemistry, Signal Transduction

Purity

99.75% (May vary between batches)

Solubility

DMSO:45 mg/mL (295.76 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (13.14 mM)