7-Amino-4- (trifluoromethyl) coumarin
7-Amino-4- (trifluoromethyl) coumarin (Coumarin 151) is a small molecule antagonist of the HTR1E serotonin receptor and the GALR2 galanin receptor, and it also inhibits HSD17B4 with an IC50 of 21 μM. This compound is utilized in biochemical research for studying receptor function and enzyme activity in vitro.
Product Specifications
CAS Number
53518-15-3
Product Name Alternative
Coumarin151, Coumarin-151, Coumarin 151, AFC, 5HT Receptor, 7 Amino 4 (trifluoromethyl) coumarin, 7Amino4 (trifluoromethyl) coumarin, 7-Amino-4- (trifluoromethyl) coumarin, 5HTReceptor, HTR1E, Inhibitor, inhibit
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.31% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:50 mg/mL (218.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.73 mM)
Smiles
NC1=CC=C2C (OC (=O) C=C2C (F) (F) F) =C1
Molecular Formula
C10H6F3NO2
Molecular Weight
229.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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