Irisolidone
Irisolidone is a potent small-molecule inhibitor of volume-regulated anion channel (VRAC) currents, demonstrating high efficacy with IC50 values ranging from 5 to 13 μM. This compound is a valuable research tool for investigating VRAC's role in cellular volume regulation, apoptosis, and cancer cell proliferation in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2345-17-7
Product Name Alternative
Chloride channel, Chloride Channel, Chloridechannel, Cl? Channels, NFκB, NF-kB, NFkB, NF-Κb, NF-κB, inhibit, Irisolidone, ILReceptor, IL Receptor, hepatoprotective, Inhibitor, VRAC, TNF-α
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.41% (May vary between batches)
Solubility
DMSO:3.15 mg/mL (10.02 mM)
Smiles
COc1ccc (cc1) -c1coc2cc (O) c (OC) c (O) c2c1=O
Molecular Formula
C17H14O6
Molecular Weight
314.29
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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