Irisolidone

Irisolidone is a potent small-molecule inhibitor of volume-regulated anion channel (VRAC) currents, demonstrating high efficacy with IC50 values ranging from 5 to 13 μM. This compound is a valuable research tool for investigating VRAC's role in cellular volume regulation, apoptosis, and cancer cell proliferation in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2345-17-7

Product Name Alternative

Chloride channel, Chloride Channel, Chloridechannel, Cl? Channels, NFκB, NF-kB, NFkB, NF-Κb, NF-κB, inhibit, Irisolidone, ILReceptor, IL Receptor, hepatoprotective, Inhibitor, VRAC, TNF-α

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.41% (May vary between batches)

Solubility

DMSO:3.15 mg/mL (10.02 mM)

Smiles

COc1ccc (cc1) -c1coc2cc (O) c (OC) c (O) c2c1=O

Molecular Formula

C17H14O6

Molecular Weight

314.29

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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