Ingenol mebutate
Ingenol mebutate is a potent, selective activator of multiple PKC isoforms (α, β, γ, δ, ε) with sub-nanomolar affinity. This compound demonstrates significant anti-inflammatory and anti-tumor properties, supporting its use in research models for actinic keratosis, non-melanoma skin cancer, and related inflammatory pathways.
Product Specifications
CAS Number
75567-37-2
Product Name Alternative
CD4, Ingenol mebutate, Ingenol 3-Angelate, HIV, HIV Protease, HIVProtease, gp120, gp120/CD4, PKC, PEP005, PEP-005, PEP 005
Field of Research
Purity
99.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.66 mM) ; DMSO:90 mg/mL (209.04 mM)
Smiles
C\C=C (\C) C (=O) O[C@H]1C (C) =C[C@@]23[C@H] (C) C[C@@H]4[C@H] ([C@H] (C=C (CO) [C@@H] (O) [C@]12O) C3=O) C4 (C) C
Molecular Formula
C25H34O6
Molecular Weight
430.53
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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