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O-Nornuciferine

O-Nornuciferine is a small molecule that potently blocks the hERG potassium channel in vitro, with an IC50 of 2.89 μM in HEK293 cells. This aporphine alkaloid is used in cardiovascular safety pharmacology and electrophysiology research to study compound-induced arrhythmia risks.

Product Specifications

CAS Number

3153-55-7

Product Name Alternative

KcsA, inhibit, Inhibitor, O Nornuciferine, ONornuciferine, O-Nornuciferine, hERG, PotassiumChannel, Potassium Channel

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.86% (May vary between batches)

Solubility

DMSO:50 mg/mL (177.71 mM)

Smiles

[H][C@]12Cc3ccccc3-c3c (OC) c (O) cc (CCN1C) c23

Molecular Formula

C18H19NO2

Molecular Weight

281.35

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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