O-Nornuciferine
O-Nornuciferine is a small molecule that potently blocks the hERG potassium channel in vitro, with an IC50 of 2.89 μM in HEK293 cells. This aporphine alkaloid is used in cardiovascular safety pharmacology and electrophysiology research to study compound-induced arrhythmia risks.
Product Specifications
CAS Number
3153-55-7
Product Name Alternative
KcsA, inhibit, Inhibitor, O Nornuciferine, ONornuciferine, O-Nornuciferine, hERG, PotassiumChannel, Potassium Channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.86% (May vary between batches)
Solubility
DMSO:50 mg/mL (177.71 mM)
Smiles
[H][C@]12Cc3ccccc3-c3c (OC) c (O) cc (CCN1C) c23
Molecular Formula
C18H19NO2
Molecular Weight
281.35
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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