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6-Bromo-2-hydroxy-3-methoxybenzaldehyde

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is a potent small molecule inhibitor of the endoplasmic reticulum stress sensor IRE1α, exhibiting an IC50 of 0.08 μM. It is a valuable research tool for studying the unfolded protein response (UPR) in cellular models of neurodegeneration, cancer, and metabolic diseases.

Product Specifications

CAS Number

20035-41-0

Product Name Alternative

Inhibitor, Inositol requiring enzyme 1, inhibit, NSC 95682, IRE1, IRE1α, NSC95682, NSC-95682, 6 Bromo 2 hydroxy 3 methoxybenzaldehyde, 6Bromo2hydroxy3methoxybenzaldehyde, 6-Bromo-2-hydroxy-3-methoxybenzaldehyde

Field of Research

Cell Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.66 mM) ; DMSO:50 mg/mL (216.41 mM)

Smiles

C (=O) C1=C (O) C (OC) =CC=C1Br

Molecular Formula

C8H7BrO3

Molecular Weight

231.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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