6-Bromo-2-hydroxy-3-methoxybenzaldehyde
6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is a potent small molecule inhibitor of the endoplasmic reticulum stress sensor IRE1α, exhibiting an IC50 of 0.08 μM. It is a valuable research tool for studying the unfolded protein response (UPR) in cellular models of neurodegeneration, cancer, and metabolic diseases.
Product Specifications
CAS Number
20035-41-0
Product Name Alternative
Inhibitor, Inositol requiring enzyme 1, inhibit, NSC 95682, IRE1, IRE1α, NSC95682, NSC-95682, 6 Bromo 2 hydroxy 3 methoxybenzaldehyde, 6Bromo2hydroxy3methoxybenzaldehyde, 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
Field of Research
Cell Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.66 mM) ; DMSO:50 mg/mL (216.41 mM)
Smiles
C (=O) C1=C (O) C (OC) =CC=C1Br
Molecular Formula
C8H7BrO3
Molecular Weight
231.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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