GI254023X
GI254023X is a potent dual inhibitor of MMP9 and ADAM10, exhibiting IC50 values of 2.5 nM and 5.3 nM, respectively. It demonstrates anti-proliferative and pro-apoptotic activity in Jurkat cells and has been utilized in research on cancer, inflammation, and Alzheimer's disease in both cellular and animal models.
Product Specifications
CAS Number
260264-93-5
Product Name Alternative
ADAM10, Inflammation related, Inflammationrelated, Immunology related, Immunologyrelated, inhibit, MMP-9, MMP, Inhibitor, Matrix metalloproteinases, GI254023X, GI 254023X, GI 4023, GI-254023X, GI4023, GI-4023, SRI 028594, SRI028594, SRI-028594
Field of Research
Immunology & Inflammation, Protein Biochemistry
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.22 mM) ; DMSO:117.5 mg/mL (300.13 mM)
Smiles
CNC (=O) [C@@H] (NC (=O) [C@H] (CCCc1ccccc1) [C@H] (C) N (O) C=O) C (C) (C) C
Molecular Formula
C21H33N3O4
Molecular Weight
391.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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