O6-Benzylguanine
O6-Benzylguanine is a potent and irreversible inactivator of the DNA repair protein O6-alkylguanine-DNA alkyltransferase (AGT) . It is widely used in cancer research to sensitize tumor cells to alkylating agents in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
19916-73-5
Product Name Alternative
DNA Synthesis, DNA/RNA Synthesis, DNAAlkylation, DNA Alkylation, DNASynthesis, cyclin, Apoptosis, antineoplastic, analog, cancer, O6 Benzylguanine, O6-alkylguanine-DNA-alkyltransferas, O6Benzylguanine, O-6-Benzylguanine, O6-Benzylguanine, p21, PARP1, inhibit, p53, pancreatic, guanine, Inhibitor, RNASynthesis, RNA Synthesis, transcriptional
Field of Research
Cell Biology, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:60 mg/mL (248.7 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.29 mM)
Smiles
O (CC1=CC=CC=C1) C2=C3C (=NC (N) =N2) N=CN3
Molecular Formula
C12H11N5O
Molecular Weight
241.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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