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Talnetant

Talnetant (SB-223412) is a selective, brain-penetrant antagonist of the neurokinin 3 (NK3) receptor. It is used in research to investigate the modulation of dopaminergic pathways, with applications in studying psychiatric and neurological conditions in both in vitro and in vivo models.

Product Specifications

CAS Number

174636-32-9

Product Name Alternative

Inhibit, NK3, NK3 receptor, NK receptor, Neurokinin receptor, Neurokinin Receptor, Neurokininreceptor, hNK-2, Inhibitor, SB223412, SB-223412, SB 223412, schizophrenia, Talnetant, Tachykinin receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

≥95% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.46 mM) ; DMSO:100 mg/mL (261.47 mM)

Smiles

CC[C@H] (NC (=O) c1c (O) c (nc2ccccc12) -c1ccccc1) c1ccccc1

Molecular Formula

C25H22N2O2

Molecular Weight

382.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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