[D-Trp7,9,10]-Substance P
Product Specifications
UNSPSC Description
[D-Trp7,9,10]-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/d-trp7-9-10-substance-p.html
Solubility
10 mM in DMSO
Smiles
C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCSC)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(=O)[C@H]6N(C([C@H](CCCNC(=N)N)N)=O)CCC6)CCCCN)=O)CCC5)CCC(N)=O)=O)CCC(N)=O)=O)=O)CC7=CC=CC=C7)=O)C=8C=9C(NC8)=CC=CC9
Molecular Weight
1588.88
References & Citations
[1]Eardley D, et al. Both substance P agonists and antagonists inhibit ion conductance through nicotinic acetylcholine receptors on PC12 cells. Eur J Pharmacol. 1985;114(1):101-104.|[2]Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1375/D-Trp7-9-10-Substance-P-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1375/
Clinical Information
No Development Reported
CAS Number
89430-38-6
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