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Trifarotene

Trifarotene (CD5789) is a selective RARγ agonist, exhibiting 65-fold and 16-fold greater potency for RARγ (EC50=7.7 nM) over RARα and RARβ subtypes, respectively. This compound is a valuable research tool for studying retinoid signaling in models of dermatology and oncology, both in vitro and in vivo.

Product Specifications

CAS Number

895542-09-3

Product Name Alternative

Inhibitor, inhibit, CD5789, CD-5789, CD 5789, Autophagy, acne, selective, RARγ, RAR, RAR/RXR, Retinoid X receptors, RetinoidReceptor, Retinoic acid receptors, Retinoid Receptor, trifarotene

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.51% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.88 mM) ; DMSO:200 mg/mL (435.18 mM)

Smiles

CC (C) (C) c1cc (ccc1N1CCCC1) -c1cc (ccc1OCCO) -c1ccc (cc1) C (O) =O

Molecular Formula

C29H33NO4

Molecular Weight

459.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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