Trifarotene
Trifarotene (CD5789) is a selective RARγ agonist, exhibiting 65-fold and 16-fold greater potency for RARγ (EC50=7.7 nM) over RARα and RARβ subtypes, respectively. This compound is a valuable research tool for studying retinoid signaling in models of dermatology and oncology, both in vitro and in vivo.
Product Specifications
CAS Number
895542-09-3
Product Name Alternative
Inhibitor, inhibit, CD5789, CD-5789, CD 5789, Autophagy, acne, selective, RARγ, RAR, RAR/RXR, Retinoid X receptors, RetinoidReceptor, Retinoic acid receptors, Retinoid Receptor, trifarotene
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.51% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.88 mM) ; DMSO:200 mg/mL (435.18 mM)
Smiles
CC (C) (C) c1cc (ccc1N1CCCC1) -c1cc (ccc1OCCO) -c1ccc (cc1) C (O) =O
Molecular Formula
C29H33NO4
Molecular Weight
459.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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