Tenapanor
Tenapanor (RDX 5791) is a selective NHE3 inhibitor that modulates sodium absorption in the gut and kidney. It is utilized in preclinical research for studying sodium-handling disorders, with applications in both in vitro assays and in vivo models to investigate its mechanism and therapeutic potential.
Product Specifications
CAS Number
1234423-95-0
Product Name Alternative
Sodium/hydrogen Exchanger, Sodium Channel, SodiumChannel, Sodium-hydrogen Exchanger, Tenapanor, Tenapanor free base, phosphate absorption, RDX 5791, RDX5791, RDX-5791, hyperphosphatemia, Na+/H+ Exchanger (NHE), intestinal, AZD 1722, AZD1722, AZD-1722
Field of Research
Pharmacology & Drug Discovery
Purity
98.08% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:150 mg/mL (131 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.75 mM)
Smiles
CN1C[C@@H] (c2cccc (c2) S (=O) (=O) NCCOCCOCCNC (=O) NCCCCNC (=O) NCCOCCOCCNS (=O) (=O) c2cccc (c2) [C@@H]2CN (C) Cc3c (Cl) cc (Cl) cc23) c2cc (Cl) cc (Cl) c2C1
Molecular Formula
C50H66Cl4N8O10S2
Molecular Weight
1145.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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