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PSI-6130

PSI-6130 (R 1656) is a selective inhibitor of the Hepatitis C virus NS5B RNA-dependent RNA polymerase, demonstrating potent antiviral activity with a mean IC50 of 0.6 μM in replication assays. This nucleoside analog has been utilized in both in vitro mechanistic studies and in vivo preclinical research to investigate therapeutic strategies against HCV infection.

Product Specifications

CAS Number

817204-33-4

Product Name Alternative

HCV NS5B, HCV Protease, HCV, HCVProtease, Hepatitis C virus, Inhibitor, inhibit, R 1656, R1656, R-1656, PSI6130, PSI-6130, PSI 6130

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Purity

98.63% (May vary between batches)

Solubility

DMSO:50 mg/mL (192.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.72 mM)

Smiles

C[C@@]1 (F) [C@H] (O) [C@@H] (CO) O[C@H]1n1ccc (=N) [nH]c1=O

Molecular Formula

C10H14FN3O4

Molecular Weight

259.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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