Pyroxamide
Pyroxamide is a potent small molecule inhibitor of histone deacetylases (HDACs), particularly HDAC1 (IC50: 0.1-0.2 μM), exhibiting antineoplastic activity. It is widely used in cancer research to study epigenetic mechanisms, demonstrating effects in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
382180-17-8
Product Name Alternative
Inhibitor, HDAC1, HDAC, Histone deacetylases, leukemia, inhibit, Pyroxamide, Apoptosis
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.46% (May vary between batches)
Solubility
DMSO:125 mg/mL (471.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.08 mM)
Smiles
ONC (=O) CCCCCCC (=O) Nc1cccnc1
Molecular Formula
C13H19N3O3
Molecular Weight
265.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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