ATH686
ATH686 is a potent and selective FLT3 kinase inhibitor. It is a valuable research tool for studying acute myeloid leukemia (AML), demonstrating activity in both cellular assays and in vivo models of FLT3-driven disease.
Product Specifications
CAS Number
853299-52-2
Product Name Alternative
Fms like tyrosine kinase 3, FLT3, Inhibitor, inhibit, ATH686, ATH-686, ATH 686, Apoptosis, autophosphorylation, ATP-competitive, antileukemic, Cluster of differentiation antigen 135, CD135
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.07% (May vary between batches)
Solubility
DMSO:100 mg/mL (193.98 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.76 mM)
Smiles
CCN1CCN (Cc2ccc (NC (=O) Nc3ccc (Oc4ccnc (N) n4) cc3) cc2C (F) (F) F) CC1
Molecular Formula
C25H28F3N7O2
Molecular Weight
515.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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