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USP25/28 inhibitor AZ1

AZ1 is a selective, orally bioavailable, non-competitive dual inhibitor of ubiquitin-specific proteases USP25 and USP28, with IC50 values of 0.7 μM and 0.6 μM, respectively. This compound demonstrates anti-inflammatory and anti-tumor activities in research models, supporting its investigation in oncology and immunology.

Product Specifications

CAS Number

2165322-94-9

Product Name Alternative

USP25/28, USP25/28 inhibitor AZ1, USP-25/28 inhibitor AZ1, Deubiquitinase, DUBs, AZ1, AZ-1, AZ 1

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.79% (May vary between batches)

Solubility

DMSO:250 mg/mL (592.12 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.84 mM)

Smiles

OCCNCc1cc (Br) ccc1OCc1ccc (F) c (c1) C (F) (F) F

Molecular Formula

C17H16BrF4NO2

Molecular Weight

422.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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