Brepocitinib
Brepocitinib (PF-06700841) is a selective small molecule inhibitor with high potency for JAK1 and TYK2 kinases, and moderate activity against JAK2. It is widely used in preclinical research to investigate JAK/STAT signaling pathways in autoimmune and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
1883299-62-4
Product Name Alternative
Brepocitinib, Inhibitor, Janus kinase, inhibit, JAK1, JAK2, JAK3, JAK, PF-06700841, PF06700841, PF 06700841, Tyk2, Tyrosine Kinases, TyrosineKinases
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:75 mg/mL (192.6 mM) ; Ethanol:75 mg/mL (192.6 mM)
Smiles
C (=O) (N1C2CN (CC1CC2) C3=NC (NC=4C=NN (C) C4) =NC=C3) [C@H]5C (F) (F) C5
Molecular Formula
C18H21F2N7O
Molecular Weight
389.4
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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