PRN1371
PRN1371 is a potent small molecule inhibitor targeting FGFR1-4 and CSF1R with low nanomolar IC50 values. It is a valuable research tool for studying oncogenic signaling and tumor microenvironment dynamics in both cellular assays and in vivo cancer models.
Product Specifications
CAS Number
1802929-43-6
Product Name Alternative
PRN1371, PRN-1371, PRN 1371, inhibit, Inhibitor, FGFR1, FGFR2, FGFR3, FGFR4, Fibroblast growth factor receptor, FGFR, CSF-1 receptor, CSF1R, CSF-1R, colony stimulating factor 1 receptor, cFms, c-Fms
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.65% (May vary between batches)
Solubility
DMSO:12 mg/mL (21.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.56 mM)
Smiles
CNc1ncc2cc (-c3c (Cl) c (OC) cc (OC) c3Cl) c (=O) n (CCCN3CCN (CC3) C (=O) C=C) c2n1
Molecular Formula
C26H30Cl2N6O4
Molecular Weight
561.46
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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