AMG 837 calcium hydrate
AMG 837 calcium hydrate is a potent and selective GPR40 agonist (EC50 = 13 nM), exhibiting over 1000-fold selectivity against related receptors GPR41, GPR43, and GPR120. This small molecule is a valuable research tool for investigating GPR40's role in glucose homeostasis and insulin secretion in both cellular and animal models of diabetes.
Product Specifications
CAS Number
1259389-38-2
Product Name Alternative
AMG 837 calcium, AMG 837 calcium Hydrate, AMG 837 calcium hydrate, Inhibitor, insulin, GPR40, glucose, FFAR, FFA1, Free Fatty Acid Receptor, inhibit
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.07% (May vary between batches)
Solubility
DMSO:40 mg/mL (42.06 mM)
Smiles
Molecular Formula
C52H44CaF6O8
Molecular Weight
950.97
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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