Ningetinib
Ningetinib (CT-053) is a potent, orally active small molecule inhibitor targeting Axl, VEGFR2, and c-Met kinases with low nanomolar IC50 values. It is utilized in preclinical cancer research, particularly in studies investigating tumor angiogenesis, metastasis, and resistance mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1394820-69-9
Product Name Alternative
Inhibit, Ningetinib, HGFR, Inhibitor, Mer, AXL, Axl, cMet, cMet/HGFR, c-Met, c-Met/HGFR, CT053, CT-053, CT053PTSA, CT 053, TAM Receptor, TAMReceptor, Tyro3, VEGFR2, VEGFR, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.24% (May vary between batches)
Solubility
DMSO:15 mg/mL (26.95 mM)
Smiles
Cc1c (C (=O) Nc2ccc (Oc3ccnc4cc (OCC (C) (C) O) ccc34) c (F) c2) c (=O) n (-c2ccccc2) n1C
Molecular Formula
C31H29FN4O5
Molecular Weight
556.58
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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