ASTX660
Tolinapant (ASTX660) is an orally active small molecule antagonist of cIAP1/2 and XIAP. It promotes immunogenic cell death (ICD) in sensitive head and neck squamous cell carcinoma (HNSCC) models in vitro, supporting its investigation in cancer immunotherapy and apoptosis research.
Product Specifications
CAS Number
1799328-86-1
Product Name Alternative
XIAP, inhibit, Inhibitor, IAP, ASTX 660, ASTX660, ASTX-660, cIAP
Field of Research
Cell Biology
Purity
97.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (3.71 mM) ; DMSO:47 mg/mL (87.09 mM)
Smiles
C[C@@H]1CN (CC (=O) N2CC (C) (C) c3nc (CO) c (Cc4ccc (F) cc4) cc23) [C@@H] (CN2CCOC[C@H]2C) CN1
Molecular Formula
C30H42FN5O3
Molecular Weight
539.68
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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