Fulacimstat
Fulacimstat (BAY1142524) is a potent and selective chymase inhibitor, demonstrating IC50 values of 3 nM and 4 nM against hamster and human enzymes, respectively. This small molecule is a valuable research tool for investigating chymase roles in cardiovascular and fibrotic diseases in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1488354-15-9
Product Name Alternative
Chymase, BAY 1142524, BAY1142524, BAY-1142524, Fulacimstat, Inhibitor, inhibit
Field of Research
Protein Biochemistry
Purity
99.77% (May vary between batches)
Solubility
DMSO:5 mg/mL (10.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.05 mM)
Smiles
Cn1c2ccc (cc2oc1=O) -n1cc (C (O) =O) c (=O) n ([C@@H]2CCc3c2cccc3C (F) (F) F) c1=O
Molecular Formula
C23H16F3N3O6
Molecular Weight
487.38
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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