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ONO-8590580

ONO-8590580 (CS-2894) is a selective negative allosteric modulator targeting the GABAA receptor α5 subunit. This compound is a valuable research tool for investigating the role of α5-containing GABAA receptors in cognitive processes and related neurological disorders, with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1802661-73-9

Product Name Alternative

Inhibit, ONO8590580, ONO-8590580, ONO 8590580, GABAReceptor, GABA Receptor, GABAA α5, Gamma-aminobutyric acid Receptor, Inhibitor, CS 2894, CS2894, CS-2894, γ-Aminobutyric acid Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.43% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.31 mM) ; DMSO:60 mg/mL (159.39 mM)

Smiles

Cc1c (F) c (Nc2ccc (cn2) -c2cn (C) cn2) cc2n (CC3CC3) cnc12

Molecular Formula

C21H21FN6

Molecular Weight

376.43

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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