Ningetinib Tosylate
Ningetinib Tosylate is a potent, orally active small molecule inhibitor targeting Axl, VEGFR2, and c-Met kinases with IC50 values below 10 nM. It is utilized in preclinical cancer research, particularly in studies involving tumor angiogenesis, metastasis, and resistance mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1394820-77-9
Product Name Alternative
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.77% (May vary between batches)
Solubility
DMSO:8 mg/mL (10.98 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.37 mM)
Smiles
Cc1ccc (cc1) S (O) (=O) =O.Cc1c (C (=O) Nc2ccc (Oc3ccnc4cc (OCC (C) (C) O) ccc34) c (F) c2) c (=O) n (-c2ccccc2) n1C
Molecular Formula
C38H37FN4O8S
Molecular Weight
728.79
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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